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[DOI] [PMC free article] [PubMed] [Google Scholar] Zhou W, Cao Q, Peng Y, Zhang QJ, Castrillon DH, DePinho RA, Liu ZP

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The hypothesis has expanded to include vascular dysfunction, oxidative stress, microglial activation, and impaired proteolysis (Roda et al., 2022)

Ocular Manifestations : In some cases, they can also affect the eyes