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Dehydration makes nausea significantly worse For diarrhea: Increase fiber intake gradually, not suddenly Stay hydrated with electrolyte solutions, not just plain water Avoid sugar alcohols and artificial sweeteners, which can worsen GI symptoms For constipation: Increase water intake to at least 2-3 liters daily Add magnesium citrate if needed (a gentle, effective option) Include high-fiber vegetables and fruits in your diet When to slow the escalation If you experience side effects that significantly impact your daily function, extend the current dose phase by 2-4 additional weeks before escalating

Recent evidence also shows that naltrexone is safe in patients with low-level underlying liver disease and compensated cirrhosis

[PubMed 28209389] 3546

Another systematic review found that either arginine alone or a combination of arginine and glutamine supplementation led to a reduction in wound size over a period of 220 weeks (202)

Lin X, Song X, Zhang Y, et al

NMDA antagonists as neurotherapeutic drugs, psychotogens, neurotoxins, and research tools for studying schizophrenia