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Similarly, krill oil combined with nobeletin and L-theanine ameliorated memory and cognitive deficiency in senescence-accelerated prone mouse/8 (SAMP8), showing synergistic effects on inhibition of A aggregation, neurofibrillary tangles, apoptosis, and neuroinflammation [42]

Moreover, gliotoxin can abrogate the angiogensis induced by H 2 O 2 in low concentrations, and gliotoxin can completely inhibit the angiogenic effect in immunosuppressive mice treated with cyclophosphamide via the abolishment of the production of ROS, which is mediated by gliotoxin-catalyzed reduction by the assistance of NAPDH [32]

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The function of catalase-bound NADPH

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Although a variant transketolase enzyme has been proposed to be associated with Wernicke-Korsakoff syndrome, no mutations have been found in the gene (symbol: TKT) encoding this enzyme when cloned from patients exhibiting the syndrome