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Macrophage-derived exosomes enriched in ferroptosis-inhibitory microRNAs, such as miR-485-5p or miR-214-3p, or exogenously engineered vesicles delivering FSP1, represent promising cell-specific delivery platforms (157, 188, 199, 200)
The DAC modification significantly extends its half-life, allowing for prolonged activity and making it ideal for studies on muscle growth, recovery, anti-aging, and fat metabolism
In South Florida patients presenting with metabolic syndrome, insulin resistance, or obesity-related fatigue, both deficits tend to be present simultaneously

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Leukemic cells seem to adopt the bone marrow microenvironment according to their needs and suppress normal hematopoiesis via secretion of cytokines, microRNAs and exosomes