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This is a direct consequence of slowed gastric emptying and increased gastrointestinal transit time

Aside from providing cysteine as a glutathione precursor, NAC also appears to have antioxidant properties by itself, and is a valuable sulfur donor for various metabolic needs

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The three proline residues at positions 35 (the PPP motif) rigidify the chain and hinder access by proteolytic enzymes a molecular explanation of the peptide stability in the gastrointestinal environment described in the literature

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The gut microbiota consists of approximately 10 14 cells, including prokaryotes, eukaryotes, viruses and bacteriophages, which are crucial for host metabolism, immune, and nervous system development (Cryan et al., 2019)