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This follows its role as a cytoprotection mediator transmitting the mucosal integrity maintenance to other organs therapy [1,2,3,4,5,6,7,8,9,10,11,15,27,28,29,30,33,109,124,125] in consideration of the regular dietary taking (dietary nitrate as an important source of NO in mammals [252]), and nitrate-nitrite-NO pathway (and swallowed nitrite) resulting with high NO concentration in the stomach [253]

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Elevated cAMP activates protein kinase A (PKA), which then phosphorylates and activates hormone-sensitive lipase

These findings indicate a broader scope of action for thymosin beta-4, impacting both intra- and extracellular processes

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