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Mol Psychiatry (2013).10.1038/mp.2013.138 28 AndreassenOAHarboHFWangYThompsonWKSchorkAJMattingsdalMet alGenetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

Oxidative stress, resulting from the generation of ROS, can lead to inflammation and cellular destruction and impede muscle recovery if it coincides with training adaptations (548)

These findings are suggestive of a role for increased PPARA in the BWS-hepatocytes contributing to increased fatty acid oxidation, which subsequently coincides with increase in lipid peroxidation, a marker of oxidative stress