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Also, as at the moment of writing, no randomized controlled trials (RCTs) have been conducted to specifically assess whether attenuating intestinal inflammation or barrier dysfunction improves cognitive outcomes in post-IIRI settings or related clinical conditions

123,124 Therefore, inducing moderate autophagy can be considered as a potential therapeutic strategy against AIH

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Consistently, our results showed that the levels of ROS and superoxide were significantly decreased with IMP supplementation, which may be one of the reasons why ROS accumulation is relatively lower in IMP-treated aged oocytes
