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Alpha lipoic acid (ALA) is an organosulfur fatty acid with strong antioxidant properties

Sakai Y, Nishikawa H, Enomoto H, et al

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Therefore, selenium deficiency is associated with thyroid dysfunction and increased risk of thyroid autoimmunity and nodules [65], a condition further aggravated by the fact that concurrent iodine and selenium deficiency is rather common [66, 67]

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These genetic insights may help provide context for why certain individuals show robust response to triple-agonist therapy while others require dose adjustment or alternative approaches