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The trial excluded patients with an autoimmune disease, a condition requiring immunosuppression, or a history of severe immune-related adverse events (irAEs) from treatment with ipilimumab

Relatively minor trauma results in blistering and erosions

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Uncommon symptoms include abdominal distention, nausea, emesis, and diarrhea (Table 1)

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) in plants maintenance of structural individuality and functional blend

The best treatment for dark under-eye circles varies based on the cause