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High fat diet and its effects on cognitive health: alterations of neuronal and vascular components of brain

The accumulation of 4-HNE-protein adducts in tissues reflects the degree of oxidative damage and may provide insight into the progression of the disease [145]

To determine the percentage of bromodeoxyuridine (BrdU) positive cells, 10 M BrdU was then added to culture media for an additional 5 h while for cell cycle analysis, 10 M BrdU was added for only 30 min

& Tyagi, A

Similar trends were observed in the kidneys and lungs, where ascorbate levels decreased, and dehydroascorbate levels increased

The optimized nanoformulation not only enhanced ASI accumulation in the CNS but also exhibited dual therapeutic effects: (1) marked reduction of demyelination and (2) promotion of myelin regeneration