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Dario Zamboni (University of So Paulo, Ribeiro Preto, Brazil)

These mutations not only activate downstream signaling pathways, such as PI3K-AKT and MAPK, but also reprogram tumor metabolism to favor glycolysis

Despite preclinical studies showing the therapeutic promise of CoQ10 against brain cancers, no reports of randomized clinical trials are available so far regarding clinical use of CoQ10 in brain cancer patients

Currently, several CPP-based therapeutics have been under clinical trials for their potential applications in the therapy and diagnostics of human diseases, such as solid tumor, glioma, CNS tumor, and muscular dystrophy (

Exclusion Criteria: diarrhea or oral antibiotic intake within the previous 4 weeks
