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REFERENCES ABOUT THIS ARTICLE Cite this article: Wang Y., Feng Z

See Right Thromboxane A2 [TXA2] bind to the thromboxane A2 receptor [TXA2R] resulting in a number of events that can potentially lead to interruption of blood flow (thrombosis) (e.g., vasoconstriction and platelet aggregation)

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Non-enzymatic processes and metal-catalyzed chemistry Non-enzymatic reactions become prominent when redox homeostasis is strained, creating ROS independently of dedicated enzymes: autoxidations arise as semiquinones and reduced flavins pass single electrons to O 2 , yielding O 2 that dismutates to H 2 O 2 and seeds local chain reactions in metabolically intense niches (Hayyan et al