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While changes in serotonin activity are not thought to play a significant role in mediating somatic signs of alcohol withdrawal, its general role in regulating mood and affect suggests serotonin may contribute to withdrawal-related dysphoria, as well as motivational effects of alcohol

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Compared to mouse macrophages, the primary bovine PBMC used in this study constituted a heterogenous cell population, comprising a monocyte population of approximately 10% as shown by hematological analyses (52), which enables them to recognize LPS and respond directly to it

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