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Supporting this interpretation, fasting glucose, plasma insulin levels, and HOMA-IR were comparable between Gpr146 / and Gpr146 +/+ animals (Supplementary Fig
10.1080/13813455.2020.1727927 26 Chen JJ.DengX.LinT.HuangJ.YangY.LianN
The glyoxylate shunt reduces endogenous ROS production, while the pentose phosphate pathway is enhanced to increase NADH levels and replenish antioxidants
Sci Rep 2016;6:18928
PMC 135491
thereby reducing excitotoxicity
