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70,71 Gerin et al established a septic lung injury model by cecum ligation and puncture in rats, showing that early administration of Quercetin reduced the levels of oxidative stress markers, such as xanthine oxidase (XO), nitric oxide (NO), and malondialdehyde (MDA), and increased the levels of antioxidant enzymes in lung tissues, leading to a reduction in oxidative stress and consequently reduced production of inflammatory factors in the lungs

Conventional activation of the pathway is initiated at the cell surface by the phosphorylation of RTKs in response to mitogen stimulation [10]

Blood Cancer 65 , e27313 (2018)

The inhibition of Notch signaling induces the dedifferentiation of BECs to LPCs, whereas the activation of Notch promotes BEC proliferation

10.1161/01.atv.14.7.1098 [DOI] [PubMed] [Google Scholar] Shen Z.-Q., Chang W.-Q., Liang L.-F., Zhang J.-R., Wang Y.-Q., Yin X., et al

Among the recruited cells, most monocytes differentiate into M2 macrophages (alternatively activated), which exhibit an anti-inflammatory phenotype