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doi:10.1016/j.ymgme.2009.04.005
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Researchers commonly hold a step longer if GI side effects are not tolerated rather than skip ahead
Keeping that distinction clear is what this guide is for

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There was increased tight junction protein expression (e.g., zonula occludens-1 (ZO-1)) and transepithelial resistance, which significantly mitigates leaky gut syndrome and stabilizes cellular junctions [18]
