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3 Therapeutic efficacy of medicinal plants in mitigating cadmium-induced toxicity Several cancer statistics reports, including Cancer Statistics (American Cancer Society 2012), showed an estimated 1.64 million new cases of cancer detected and an alarming number of approximately 577,000 deaths caused by cancer in the United States of America (57), while India estimated 14.61427 million new cases of cancer detected alone in 2022 (58)

Night-time application and alternating frequency (2-3 times weekly initially) may help minimize sensory irritation and erythema in darker skin phenotypes

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Figure 6 The effects of GGC in human astrocytes is relevant for neuroprotection in AD and other neurodegenerative diseases since astrocytes represent the supporting cells in the brain and protect neurons against oxidative stress and enhance neuronal survival during cytotoxic conditions

This review is intended as a scientific overview for researchers and clinicians and does not constitute clinical recommendations

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