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Consideration The requirements for assessing the genotoxicity of pharmaceuticals differ between small molecule drugs and biotherapeutics

Normal dermal fibroblasts were seeded into a 96-well cell culture plate and have been grown to confluence in high glucose media, supplemented with 10% fetal calf serum for around 3 days

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It often starts as a painless lump in the leg, arm, head, or neck but can spread to other parts of the body, such as the lungs