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doi: 10.1016/j.phrs.2020.105263 42 LiuS.WeiZ.DengM.XianZ.LiuD.LiuG.et al

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Therefore, the results indicated that targeted suppression of the TLR4/NF-B signal path may be a significant mechanism for naringenin treating UC
Genetic or optogenetic suppression of ROS in these neurons reduces sleep, establishing a bidirectional feedback loop: wakefulness elevates oxidative burden, which triggers sleep, and sleep in turn reduces ROS levels (Kempf et al., 2019)

It was also protective against apoptotic cell death in the presence of the apoptosis inducer staurosporine (Figure 6B)
