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LINC00160 mediates chemoresistance in breast cancer by recruiting CEBPB to activate TFF3 transcription, with its knockdown suppressing drug resistance, metastasis, and tumor growth in paclitaxel/doxorubicin-resistant cells and xenograft models, correlating with poor clinical chemotherapy response [104]

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The conclusion was that alisporivir at a dose of 1200 mg twice daily for 15 days had a significant viral inhibitory effect against HCV-1, HCV-3 and HCV-4.[91] In another study in treatment-nave patients, alisporivir had potent activity against the four most prevalent genotypes of HCV (HCV-1: -4.61 1.88

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