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This route bypasses the digestive system, which is critical for a peptide like tirzepatide that would be destroyed by stomach acid and digestive enzymes if swallowed

& Cariappa, A

[PubMed] [Google Scholar] 21.Djakovic Z, Djakovic I, Cesarec V, Madzarac G, Becejac T, Zukanovic G, Drmic D, Batelja L, Zenko Sever A, Kolenc D, et al

Which is the theory that cutting your calorie intake well below your usual diet will add years to your life
