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GSTs as regulators of the MAP kinase pathway The first GST described was originally identified as ligandin due to its ability to interact covalently and noncovalently with various compounds that are not substrates for enzymatic activity, including steroids, thyroid hormones, bile acid, bilirubin, and heme (Litwack et al , 1971

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The role of miR-16 in regulating the GH/IGF1 axis represents a potential key point for further investigations within pituitary adenomas

Biochemistry 2006

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