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This uncertainty makes dose adjustment decisions difficult and can lead to unnecessary discontinuation of a compound that was not responsible

Chen J., Ye Z., Huang C., et al., Lipid NanoparticleMediated Lymph NodeTargeting Delivery of mRNA Cancer Vaccine Elicits Robust CD8+ T Cell Response, PNAS 119, no

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Nevertheless, evidence was obtained that the enzymatic reaction is also required to sustain ascorbate accumulation induced in these conditions (Hamada et al

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