elevated intracellular glutathione Human cancer-associated fibroblasts enhance levels and antagonize drug-induced prostate cancer cell death Apoptosis and glutathione: beyond an

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In addition to ALS pathology, it was also observed that microglia become chronically activated, transforming a resting to an inflammatory phenotype 116

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Although the axons remain functional and oligodendrocytes remain active in 12-month-old mice, neuronal viability will likely decline due to reduced ATP and increased production of free radicals, perhaps resulting in degeneration with increasing age (Stahon et al., 2016)

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