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Stockwell laboratory in 2012, represents an iron-dependent, non-apoptotic cell death modality distinguished by intracellular iron accumulation and lipid peroxidation, culminating in cell membrane disruption and cellular demise ( Disrupted iron homeostasis constitutes a primary trigger for ferroptosis initiation

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a Phase II multicenter RCT as PL 14736 for mild-to-moderate ulcerative colitis (Pliva, completed but full results not published as a peer-reviewed paper)

It may be increased in renal failure

The mice received 50 mg/kg diquat in saline, or saline alone, delivered once by i.p

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