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Meldonium can reduce the gut microbiota-dependent production of TMA/TMAO from L-carnitine, thereby lowering TMAO levels and potentially delaying CKD, thereby lowering TMAO levels and potentially delaying CKD (Kuka et al., 2014)

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Given the consistently elevated Max HR values observed in our study, we reasoned that RTT patients are usually considered fragile and motor-impaired paradoxically compared to young athletes under active dynamic exercise
