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Previously, the patient was seen at his oncology clinic for evidence of cancer progression on his current chemotherapy, rituximab and polatuzumab vedotin, due to an increase in the growth of a bulky tumor on the patients back ( Figure 2 ) The patient was urgently started on a new chemotherapy regimen consisting of ifosfamide, carboplatin and etoposide

The susceptibility of vascular cells to oxidative stress is a function of the overall balance between the degree of oxidative stress and the antioxidant defense capability

doi: 10.1016/j.cbpa.2016.03.005

Jo S, Ha TK, Han S-H, Kim ME, Jung I, Lee H-W, Bae SK, Lee JS (2017) Myricetin induces apoptosis of human anaplastic thyroid cancer cells via mitochondria dysfunction

431 These FFAs support mitochondrial -oxidation and OXPHOS, providing essential energy substrates under hypoxic or nutrient-depleted conditions

For instance, for the driver mutation-dependent subtype, a combined strategy of targeted therapy and epigenetic regulation should be adopted in accordance with molecular subtypes, such as the FGFR3-mutant subtype in bladder cancer