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Published research uses varying doses depending on the model and endpoint

Table Of Contents Metformin And Vitamin B12 Deficiency The Evidence A long term study on Metformin and Vitamin B12 deficiency showed low levels of B12 and increased levels of anemia after the 5 year study

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The risk of vitamin B12 deficiency is higher in patients with T2D receiving high metformin doses for an extended period or in the presence of other known risk factors associated with vitamin B12 deficiency, such as advanced age and regular use of acid-suppressing medications

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