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Carion et al., TB-500 and Ciprofloxacin Adjunctive Therapy Improves Pseudomonas aeruginosa-Induced Keratitis, Cells, 7(10), 2018

Aquacobalamin (H 2 OCbl) brominated at the C10-position of the corrin reacts with GSH to give Cbl(II) via GSH complexation and subsequent reaction of this complex with a second GSH molecule, whereas unmodified H 2 OCbl generates glutathionyl-Cbl, which is resistant to further reduction by GSH

Isothiocyanates likely inhibit the expression and function of hypoxia inducible factors (HIFs) that control angiogenesis, as reported in endothelial cells and malignant cell lines (35)

Notably, the inherent susceptibility of pancreatic -cells to ferroptosis provides a mechanistic basis for DM progression, while hyperglycemia reciprocally promotes systemic iron accumulation, thereby establishing a self-reinforcing cycle

Alves F, Lane D, Nguyen TPM, Bush AI, Ayton S

two different cell lines) or six replicates per condition (GAPDH inhibition