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(September 2005)

International Psychogeriatrics

In 1951, Giulio Cantoni purified NNMT partially and characterized its methyltransferase activity for the first time [3]

Esposito G, Dottori L, Pivetta G, et al
biology Nicotinamide regulation Cellular signaling Enzyme function Cellular bioenergetics Methylation pathways Mechanism of Action 5-Amino-1MQ selectively inhibits the enzyme nicotinamide N-methyltransferase (NNMT), which plays a key role in nicotinamide utilization and cellular methylation pathways

J Psychosom Res
