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In contrast, -LA improved hyperinsulinemia and the higher levels of free fatty acids of the T2DM rats [129], increases antioxidant defense through Nrf2, and reduces inflammation in T2DM (decreases TNF- and Inhibit the expression of NLRP3 and downstream inflammatory factors IL-18 and IL-1) to prevent liver steatosis and relieve HFD-induced liver lipid accumulation in T2DM rats (Table 7)

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Tests measuring these electrical signals are gaining popularity and may help refine the diagnosis of vertigo, although variability in the different available methods remains a challenge

Intracellular glutamate accumulation inhibits system Xc activity, reducing cystine uptake, which leads to impaired glutathione (GSH) synthesis and diminished antioxidant capacity

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