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Hum Mol Genet 2013

doi: 10.3389/fnins.2018.00049 57

A clinical phase 2 trial is currently evaluating this compound as a single agent and in combination with endocrine therapy in patients with HR+, HER2 breast cancer and other cancer types

Importantly, the genetic and pharmacological inhibition of MT-1G enhances the anticancer activity of sorafenib in vitro and tumor xenograft models (Sun et al., 2016a)

Lancet 399 , 22002211 (2022)

On day 10 post-plating, tissue culture plates were coated with 20 g/ml fibronectin (Corning) and 80 g/ml Collagen IV (Advanced Biomatrix) or with 400 g/ml collagen IV and 100 g/ml fibronectin for transwell inserts in water for 24 h at 37C