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Gallois L, Fiallo M, Garnier-Suillerot A

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Am J Physiol Endocrinol Metab (2012) 302:E7786

Parasite and disease control is critically dependent on interferon (IFN)-producing type 1 T helper (Th1) cells and macrophages expressing type 2 nitric oxide synthase (NOS2), whereas non-healing, chronic CL has been linked to the expansion of interleukin (IL)-4-secreting Th2 cells, IL-10-producing CD4 + T cells and the expression of arginase 1 (ARG1) (Bogdan et al., 2024