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Long-chain fatty acids (LCFAs) cannot directly cross the mitochondrial membrane because of their high polarity and are activated to long-chain acyl-CoA by acyl-CoA synthetase (ACS)

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Biogerontology 2: 165171, 2001

Effects of carob (Ceratonia siliqua) on sperm quality, testicular structure, testosterone level and oxidative stress in busulfan-induced infertile mice

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Research has shown that it is non-toxic and even cardioprotective, possibly due to its ability to stabilize protein structure and the osmotic pressure in cells