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Description
The skin is composed of two layers: the epidermal outer layer is highly cellular and provides the barrier function, and the inner dermal layer ensures strength and elasticity and gives nutritional support to the epidermis

Cholesteryl esters are hydrolyzed by pancreatic cholesteryl ester hydrolase (cholesterol esterase), which produces cholesterol plus free fatty acids (see Figure 15.2)

Nutritional regulation of microbiota-derived metabolites: implications for immunity and inflammation
MC4 receptor activation has been explored in studies related to neuroendocrine signaling and energy balance regulation

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