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Inhibition of mutant KRAS-driven overexpression of ARF6 and MYC by an eIF4A inhibitor drug improves the effects of anti-PD-1 immunotherapy for pancreatic cancer
Blood transfusion is required if there is severe anemia
Moreover, due to the differential RT sensitivity among immune cells, RT may cause a direct decrease in the ratio of cytotoxic T cells to regulatory T cells (Tregs) 8 , accompanied by the upregulation of cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) 9
doi: 10.1038/s41594-018-0148-z 258 ZhangX.LiX.XuH
Winkelmann, R
Pilz J, Meineke I, Gleiter C
