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Dolhain, R

10.1016/S0162-0134(00)80022-7 10.1016/S0162-0134(00)80022-7 [DOI] [PubMed] [Google Scholar] Pei J, Pan X, Wei G, Hua Y (2023) Research progress of glutathione peroxidase family (GPX) in redoxidation

528 It has improved the quality of eye redness and tear film in human and animal models

Other effects less frequently reported include: metabolic, gastrointestinal, cardioprotective, antihypertensive, photoprotective, anabolic, hepatoprotective, proangiogenic, antithrombotic and antiallergic

As Lissoni et al works reported, Melatonin is useful in chemotherapy of cancer patient with poor clinical condition [96], advanced cancer patient with normal clinical status [96] and improve the efficacy of anthracyclines, cisplatin, 5fluorourcil, etoposide, gemcitabine, taxanes, raltitrexedand, isofosfamide [96,97].] Melatonin through numerous biological mechanisms is able to influence hosttumor interactions which may change both tumor and host characteristics [98- 100]

ALDH2 functions as a potent scavenger of ROS (26)