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Pb exposure has been widely associated with increased generation of ROS and reactive nitrogen species (RNS), mainly due to its interference with mitochondrial respiration and its ability to displace essential divalent cations (e.g., Ca 2+ and Zn 2+ ) [62,97]

FIGURE 3 However, for the three TMD type markers, GST-EGFP-TMD ITB3 , GST-EGFP-TMD ITAV, and GST-EGFP-TMD ITA5 , cell sorting did not significantly increase the positive cell ratio in K-562 cells and only function slightly in Lenti-X 293T cells (Figures 3A,B)

2021 Apr 14:1-39
Int J Mol Med 54:77

Your body also has something called first-pass metabolism, which basically means your liver gets first dibs on processing anything you swallow
Cancer Cell (2011) 20(6):70114
