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[DOI] [PubMed] [Google Scholar] 77.Roessler M., Rollinger W., Palme S., et al

Vitamin B12 binds to the protein in the foods we eat

Chronic users of certain medications, such as metformin (used to treat diabetes) or proton pump inhibitors (used for acid reflux)

IJMS 21, 7698

Importantly, NNMTi is highly selective and has no inhibitory effect on other SAM-dependent methyltransferases or NAD + salvage pathway enzymes

Clinical trials confirmed no IGF-1 elevation and no negative impact on glucose metabolism, even during 24-week treatment periods
