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Sandoval and Klaus Weber reported in 1978 that large microtubule-associated proteins MAP1 and MAP2 (that are crucial for tubulin assembly) are rapidly degraded in crude brain extracts by a calcium-dependent protease, which does not affect tubulin, and this event results in the permanent loss of tubulin polymerization (Sandoval and Weber, 1978)

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doi-org.reed.idm.oclc.org/10.1111/j.1529-8817.2005.00086.x

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TNBC, triple-negative breast cancer

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Thus, a physiological role has been proposed for Lp(a) in binding and transporting oxPL in the plasma (251)

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