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Current multi-epitope subunit vaccines against SARS-CoV-2 utilizing synthetic peptides are unfeasible for large-scale immunizations

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Conventional therapeutic approaches, including aminosalicylates, corticosteroids, immunosuppressants, and biological agents, face significant limitations including premature drug release, systemic toxicities, narrow therapeutic windows, and inadequate colonic accumulation

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Alcohol-related symptoms were assessed using the Alcohol Hangover Severity Scale (AHSS)