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Adding AOD-9604 should not make nausea worse because it has nothing to do with gastric emptying or appetite hormones

Conlon N, et al

MOTS-c and 5-Amino-1MQ target upstream metabolic pathways (AMPK activation and NAD+ preservation) that enhance energy expenditure and fat oxidation independent of appetite or intake

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These neuropathic symptoms can sometimes be misinterpreted as joint pain, particularly when affecting the hands, wrists, knees, or ankles