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Epigenetics, oxidative stress, and Alzheimer disease
Decreased Keap-1 expression, Aand increased HO-1 and NQO-1 expression
[PubMed | ClinicalTrials.gov | DOI] Garvey WT, Batterham RL, Bhatt DL, et al
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Liu H, Forouhar F, Seibt T, Saneto R, Wigby K, Friedman J, Xia X, Shchepinov MS, Ramesh SK, Conrad M, Stockwell BR
Inactivation of mitochondrial electron transport chain complexes and/or inactivation of the [4Fe4S] cluster in mitochondrial aconitase by intracellular oxidants is sufficient to stimulate cellular iron sulfur signaling [32]
