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As a key regulator of cellular physiology and pathology, PKM2 is increasingly recognized as a central player in CNS inflammatory diseases (Fig

TABLE 4 Provided herein are methods for preparing a conjugate comprising a protein (e.g.,an antibody or antigen-binding fragment thereof) and one or more immunomodulating oligonucleotides linked via one or more glutamine residues as shown in the structure of Formula (A), (A1), (A2), (B), or (B1)

For the majority of biologics, mean all-cause cost per patient for inpatient hospitalization, ED visits, outpatient visits and total medical costs decreased during follow-up compared with baseline (Table 2)

The hemp seed oil was more abundant in unsaturated acids compared to milk thistle seed oil (Figure 7)

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