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Saunders CR, Das SK, Ramesh A, Shockley DC, Mukherjee S
At the mechanistic level, H exerts neuroprotective effects through three core mechanisms: (1) selective scavenging of toxic ROS, such as -OH and ONOO-, along with the activation of the Nrf2/ARE pathway to enhance endogenous antioxidant defenses

Up to date, there is no effective treatment to interrupt the neurodegeneration, although alternatives have been studied to prevent or reduce the progression of PD
J Thorac Cardiovasc Surg 151(4):1012-3, 2016
doi: 10.1182/blood-2005-03-1257 148 RezvaniKMielkeSAhmadzadehMKilicalYSavaniBNZeilahJet al
doi: 10.3389/fonc.2023.1168321 32
