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DVTs are usually caused by: slowing of the blood flow in your deep veins injuries to your blood vessels conditions or other factors that increase blood clotting Factors that can increase your risk of having DVT are: having an injury such as a bone fracture being in hospital for surgery or a major illness sitting still for a long time, such as during a long-haul flight having conditions such as cancer or heart failure taking treatments such as the oral contraceptive pill ('the pill') or hormone replacement therapy that contain the hormone oestrogen being pregnant having a genetic condition that makes your blood more likely to clot Other factors that can increase your risk include: being overweight smoking A DVT can sometimes happen with no obvious cause