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ATG4C knockdown in T98G glioma cells inhibited autophagy, enhancing the cell cycle arrest and promoting apoptosis through the production of ROS, the expression of p21, p53, and Bax, and decreased levels of Bcl-2 [163]

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The plates were briefly stirred and the absorbance was monitored in kinetic mode in a plate reader SpectraMax ABS Plus (Molecular Devices)

Under the same conditions, a product with a similar electron ionization (EI)-MS fragmentation pattern as MeHgCl (Fig

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c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in chronic myelogenous leukemia CD34+ hematopoietic progenitor cells