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doi: 10.3390/ijms23073645, 43

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One obvious drawback of these locking solutions is that the large organic drugs cannot pass through the wall of a catheter and therefore cannot protect the exterior surface of the catheter at all although bacterial contamination may occur extraluminally due to open surgical site contamination, exit-site infection or bacteremia caused by other sources [66]

Journal of Hepatology , 62 , 720733

However, some fungal pathogens and fungal-like oomycetes have a unique SOD, such as Cu-SODs (SOD5)