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Furthermore, flavokavains A and B were shown to have immunomodulatory functions, such as the stimulation of splenocyte proliferation and the secretion of IL-2 and TNF- in harvested splenocytes, as well as an increase in the subsets of T cell populations in BALB/c mice, with flavokavain B being more potent than flavokavain A (30 g/mL) [59]

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